Sci. STKE, 10 August 2004
CASPASES Programming Cell Death in Plants
Programmed cell death serves many useful functions--it helps in remodeling tissues during development and when organisms respond to environmental challenges. In virally infected plants, infected cells are killed by programmed cell death during the hypersensitive response. However, the signature caspases that promote programmed cell death found in animals have not been found in plants. Hatsugai et al. now identify VPE, a vacuolar processing enzyme, as a critical component of programmed cell death in tobacco plants. It seems that each plant cell, confined within its rigid cell wall, contains within its own vacuole the seeds of its own destruction.
N. Hatsugai, M. Kuroyanagi, K. Yamada, T. Meshi, S. Tsuda, M. Kondo, M. Nishimura, I. Hara-Nishimura, A plant vacuolar protease, VPE, mediates virus-induced hypersensitive cell death. Science 305, 855-858 (2004). [Abstract] [Full Text]
Citation: Programming Cell Death in Plants. Sci. STKE 2004, tw287 (2004).
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