Focus IssueThe Dynamics of Gene Expression
Nancy R. Gough*
Managing Editor of Science's STKE, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.
Summary:
It is gene expression that defines a cell's identity. Science, Science's Science of Aging Knowledge Environment (SAGE KE), and Science's STKE focus attention on the highly dynamic nature of gene expression. Mechanisms governing selective gene expression in multigene families, as well as those by which cis- and trans-acting factors contribute to regulation of gene expression, are topics under discussion. In addition, new methodologies allow researchers to gain insight into gene expression at the level of single cells and provide a glimpse at the real-time interactions among proteins and DNA.
*Contact information. E-mail, ngough{at}aaas.org