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Sci. STKE, 9 November 2004
Vol. 2004, Issue 258, p. pl15
[DOI: 10.1126/stke.2582004pl15]

PROTOCOLS

Spectral Analysis of Calcium Oscillations

Per Uhlén*

Departments of Pharmacology, Cell and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA or Department of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden

Abstract: Calcium (Ca2+) oscillations are universal signals exploited by cells to regulate a vast number of cellular processes. Frequency and amplitude, the key features of oscillating waves, can yield information that can be decoded by intracellular processes. Analysis and quantification of Ca2+ oscillations are crucial for understanding the general concept of Ca2+ signaling. This protocol presents a method for performing spectral analysis of Ca2+ oscillations using MATLAB software.

*Contact information. Department of Pharmacology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520-8066, USA. Telephone, +1-203-737-1158; fax, +1-203-737-2027; e-mail, per.uhlen@yale.edu. Alternatively, Department of Woman and Child Health, Karolinska Institutet, Astrid Lindgren Children’s Hospital Q2:09, S-171 76 Stockholm, Sweden. Telephone, +46-8-51777339; fax, +46-8-51777328; e-mail, per.uhlen{at}kbh.ki.se

Citation: P. Uhlén, Spectral Analysis of Calcium Oscillations. Sci. STKE 2004, pl15 (2004).

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