Sci. STKE, 9 November 2004
SECRETION Candid Camera on Secretion
The interaction of SNARE proteins, like SNAP25, syntaxin, or synaptobrevin, is a key event in the fusion intracellular membranes, such as when secretory vesicles fuse with the plasma membrane during regulated secretion. An et al. engineered a series of fluorescent SNAP25 analogs that change color when SNAREs interact in living cells. In time-resolved recordings, SNARE complexes could be observed to assemble and disassemble when single cells were stimulated to secrete.
Citation: Candid Camera on Secretion. Sci. STKE 2004, tw409 (2004).
Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882