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Sci. STKE, 29 March 2005
Vol. 2005, Issue 277, p. pe12
[DOI: 10.1126/stke.2772005pe12]

PERSPECTIVES

Food Fight: The NPY-Serotonin Link Between Aggression and Feeding Behavior

Ronald B. Emeson1,2* and Michael V. Morabito2

1Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
2Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

Abstract: Aggressive behavior in mammals is linked to feeding. Interactions between neuropeptide tyrosine (NPY) and serotonergic neurons provide this link. Studies of aggressive behavior in mice in which the Y1 subtype of NPY receptor was knocked out further define the synaptic circuits responsible for the interrelation of these instinctive behaviors.

*Corresponding author. E-mail: ron.emeson{at}vanderbilt.edu

Citation: R. B. Emeson, M. V. Morabito, Food Fight: The NPY-Serotonin Link Between Aggression and Feeding Behavior. Sci. STKE 2005, pe12 (2005).

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