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Sci. STKE, 12 April 2005
Vol. 2005, Issue 279, p. tr11
[DOI: 10.1126/stke.2792005tr11]


G Protein–Coupled Receptors

Stuart C. Sealfon*

Department of Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA.

Abstract: This Teaching Resource provides lecture notes and slides for a class covering G protein–coupled receptors (GPCRs) and is part of the course "Cell Signaling Systems: A Course for Graduate Students." The lecture begins with a discussion of the major classes of GPCRs and then proceeds to describe the mechanisms of receptor diversity, ligand interaction, desensitization, coupling, and mutations associated with human diseases.

*Contact information. E-mail, stuart.sealfon{at}

Citation: S. C. Sealfon, G Protein–Coupled Receptors. Sci. STKE 2005, tr11 (2005).

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882