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Sci. STKE, 21 June 2005 EDITORS' CHOICEPLANT BIOLOGY Indirect DefensesSome plants defend against fungal infection by using the hypersensitive response, in which plant cells at the site of invasion are killed off to retard spread of the infection. The process relies upon an elicitor from the pathogen and a corresponding resistance gene in the plant. When Cladosporium fulvum infects tomato leaves, these two factors do not, however, seem to interact directly. Rooney et al. analyze the function of the plant protease Rcr3 in mediating the defense response. The pathogen avirulence factor, Avr, is secreted extracellularly, where it interacts with the tomato plant Rcr3 protease. Together, this interaction signals to the membrane-bound host resistance factor, Cf-2, to initiate plant defense responses. H. C. E. Rooney, J. W. van 't Klooster, R. A. L. van der Hoorn, M. H. A. J. Joosten, J. D. G. Jones, P. J. G. M. de Wit, Cladosporium Avr2 inhibits tomato Rcr3 protease required for Cf-2-dependent disease resistance. Science 308, 1783-1786 (2005). [Abstract] [Full Text]
Citation: Indirect Defenses. Sci. STKE 2005, tw230 (2005). The editors suggest the following Related Resources on Science sites:In Science Signaling
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882