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Sci. STKE, 24 January 2006
Vol. 2006, Issue 319, p. pe4
[DOI: 10.1126/stke.3192006pe4]

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Endothelin Action on Pituitary Lactotrophs: One Receptor, Many GTP-Binding Proteins

Richard Bertram1,2*, Joel Tabak2*, Natalia Toporikova1*, and Marc E. Freeman2,3*

1Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA.
2Program in Neuroscience, Florida State University, Tallahassee, FL 32306, USA.
3Department of Biological Sciences, Florida State University, Tallahassee, FL 32306, USA.

Abstract: The endothelins are a family of hormones that have a biphasic action on pituitary lactotrophs. The initial effect is stimulatory, followed later by inhibition that persists long after the agonist has been removed. Recent research has uncovered several G protein pathways that mediate these effects.

*Corresponding authors. E-mail, bertram{at}math.fsu.edu (R.B.); joel{at}neuro.fsu.edu (J.T.); ntoporik{at}math.fsu.edu (N.T.); freeman{at}neuro.fsu.edu (M.E.F.)

Citation: R. Bertram, J. Tabak, N. Toporikova, M. E. Freeman, Endothelin Action on Pituitary Lactotrophs: One Receptor, Many GTP-Binding Proteins. Sci. STKE 2006, pe4 (2006).

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