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Sci. STKE, 16 May 2006
Vol. 2006, Issue 335, p. tw165
[DOI: 10.1126/stke.3352006tw165]

EDITORS' CHOICE

PLANT BIOLOGY PINning Down Auxin Flow

The plant hormone auxin regulates a variety of growth and developmental responses and must be transported within the plant in an organized fashion. Petrásek et al. (see Brevia by Wisniewska and Perspective by Siberer and Leyser) now show, using inducible overexpression in plant cells and expression in human and yeast cells, that the protein PIN is responsible for the direction in which auxin flows out of the cell.

J. Petrásek, J. Mravec, R. Bouchard, J. J. Blakeslee, M. Abas, D. Seifertová, J. Wisniewska, Z. Tadele, M. Kubes, M. Covanová, P. Dhonukshe, P. Skupa, E. Benková, L. Perry, P. Krecek, O. R. Lee, G. R. Fink, M. Geisler, A. S. Murphy, C. Luschnig, E. Zazímalová, J. Friml, Pin proteins perform a rate-limiting function in cellular auxin efflux. Science 312, 914-918 (2006). [Abstract] [Full Text]

J. Wisniewska, J. Xu, D. Seifertová, P. B. Brewer, K. Ruzicka, I. Blilou, D. Rouquié, E. Benková, B. Scheres, J. Friml, Polar PIN localization directs auxin flow in plants. Science 312, 883 (2006). [Abstract] [Full Text]

T. Sieberer, O. Leyser, Auxin transport, but in which direction? Science 312, 858-860 (2006). [Summary] [Full Text]

Citation: PINning Down Auxin Flow. Sci. STKE 2006, tw165 (2006).



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