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Sci. STKE, 18 July 2006
Vol. 2006, Issue 344, p. tw243
[DOI: 10.1126/stke.3442006tw243]

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VIROLOGY Destructive Influence

Certain bacterial pathogens inject their effector proteins into the target cell to wreak havoc. Nomura et al. now show what a Pseudomonas protein does once it is inside an Arabidopsis plant cell. The virulence protein, HopM1, targets a plant defense protein, AtMIN7, by escorting that protein to its destruction by the plant's own proteasome. AtMIN7 normally functions in the vesicle trafficking that builds up a cell-wall response to pathogen invasion.

K. Nomura, S. DebRoy, Y. H. Lee, N. Pumplin, J. Jones, S. Y. He, A bacterial virulence protein suppresses host innate immunity to cause plant disease. Science 313, 220-223 (2006). [Abstract] [Full Text]

Citation: Destructive Influence. Sci. STKE 2006, tw243 (2006).

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