Sci. STKE, 23 January 2007
Genetics Finding Redox-Active Cysteines
Barbara R. Jasny
Science, AAAS, Washington, DC 20005, USA
Cysteine residues are found in a wide variety of proteins, in which they serve many functions. Identifying particular functions has required laborious individual characterization. Fomenko et al. present and experimentally verify an algorithm that can identify which cysteines act in redox reactions by searching for sporadic selenocysteine-Cys pairs in sequence databases. This methodology should assist in metagenomic analyses to identify oxidoreductase families.
Citation: B. R. Jasny, Finding Redox-Active Cysteines. Sci. STKE 2007, tw33 (2007).
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