Sci. STKE, 23 October 2007
Plant Biology The Best Offense Is Someone Elses Defense
Pamela J. Hines
Science, AAAS, Washington, DC 20005, USA
Part of the strategy that Agrobacterium uses to attack its host plant cells includes transferring part of its genome into the plant cells genome. This DNA transfer event has been effectively used as a tool for plant genetic transformation in the lab. In the natural interaction, Agrobacterium uses a complex of proteins, including both its own and the hosts, to effect the transfer of its DNA into the plant cell nucleus. One of the plants proteins, VIP1, was known to function for Agrobacterium DNA transfer, but its use to the host plant was unknown. Djamei et al. have now discovered that the plants VIP1 is supposed to function in a pathogen defense cascade. Thus, Agrobacterium derails the plants defense response by using one of the plants own effectors to carry the bacterial DNA into the plant nucleus.
Citation: P. J. Hines, The Best Offense Is Someone Elses Defense. Sci. STKE 2007, tw384 (2007).
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