Focus Issue: External and Internal Regulators of Immune Responses

John F. Foley^1* and Nancy R. Gough²

¹ Associate Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.
² Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.

Abstract: This Focus Issue of Science Signaling, which complements the Science Special Issue on Innate Immunity (http://www.sciencemag.org/special/immunity), highlights the effects of viral and bacterial components on host cells, signaling pathways involved in regulating innate immune responses, and factors that modulate the functions of dendritic cells, which are required for effective adaptive immunity.

* Corresponding author. E-mail: jfoley{at}aaas.org

The editors suggest the following Related Resources on Science sites:

In Science Signaling

EDITORS' CHOICE
Immunology
Controlling the Allergic Reaction

Leslie K. Ferrarelli (22 January 2013)
Sci. Signal. 6 (259), ec21. [DOI: 10.1126/scisignal.2003984]
 |  Abstract »

EDITORS' CHOICE
Immunology
Signal Stealer

Kristen L. Mueller (3 May 2011)
Sci. Signal. 4 (171), ec125. [DOI: 10.1126/scisignal.4171ec125]
 |  Abstract »

EDITORS' CHOICE
Host-Microbe Interactions
Why Not Take Antibiotics for the Flu?

Elizabeth M. Adler (5 April 2011)
Sci. Signal. 4 (167), ec94. [DOI: 10.1126/scisignal.4167ec94]
 |  Abstract »

EDITORS' CHOICE
Host-Pathogen Interactions
Degraded for Shock Value

Wei Wong (29 March 2011)
Sci. Signal. 4 (166), ec89. [DOI: 10.1126/scisignal.4166ec89]
 |  Abstract »

EDITORS' CHOICE
Host-Pathogen Interactions
Scaffold for Infection

Wei Wong (11 January 2011)
Sci. Signal. 4 (155), ec10. [DOI: 10.1126/scisignal.4155ec10]
 |  Abstract »

PODCASTS
Host-Pathogen Interactions
Science Signaling Podcast: 16 February 2010

George Hajishengallis and Annalisa M. VanHook (16 February 2010)
Sci. Signal. 3 (109), pc4. [DOI: 10.1126/scisignal.3109pc4]
 |  Abstract »  |  Full Text »  |  Podcast »

RESEARCH ARTICLES
Host-Pathogen Interactions
Microbial Hijacking of Complement–Toll-Like Receptor Crosstalk

Min Wang, Jennifer L. Krauss, Hisanori Domon, Kavita B. Hosur, Shuang Liang, Paola Magotti, Martha Triantafilou, Kathy Triantafilou, John D. Lambris, and George Hajishengallis (16 February 2010)
Sci. Signal. 3 (109), ra11. [DOI: 10.1126/scisignal.2000697]
 |  Editor's Summary »  |  Abstract »  |  Full Text »  |  PDF »  |  Supplementary Materials »

EDITORS' CHOICE
Host-Pathogen Interactions
Keeping the Host Live

Nancy R. Gough (2 February 2010)
Sci. Signal. 3 (107), ec41. [DOI: 10.1126/scisignal.3107ec41]
 |  Abstract »

In Science Magazine

INTRODUCTION TO SPECIAL ISSUE
Recognizing the First Responders

Kristen L. Mueller (15 January 2010)
Science 327 (5963), 283. [DOI: 10.1126/science.327.5963.283]
 |  Full Text »  |  PDF »  |  Podcast Interview »