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Sci. Signal., 8 June 2010
Vol. 3, Issue 125, p. ec176
[DOI: 10.1126/scisignal.3125ec176]

EDITORS' CHOICE

Development Making Menorahs

Stella M. Hurtley

Science, AAAS, Cambridge CB2 1LQ, UK

Highly branched neuronal processes are typical of numerous neurons. The mechanisms controlling the formation, maintenance, and regeneration of neuronal trees are poorly understood. Oren-Suissa et al. observed the development of extensively arborized neurite trees—menorahs—in two highly branched mechanosensory neurons in Caenorhabditis elegans. EFF-1, a fusion protein known to be important for cell fusion, played a key role in arborization.

M. Oren-Suissa, D. H. Hall, M. Treinin, G. Shemer, B. Podbilewicz, The fusogen EFF-1 controls sculpting of mechanosensory dendrites. Science 328, 1285–1288 (2010). [Abstract] [Full Text]

Citation: S. M. Hurtley, Making Menorahs. Sci. Signal. 3, ec176 (2010).



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