Sci. Signal., 28 September 2010
Neuroscience Discriminating Dendrites
Peter R. Stern
Science, AAAS, Cambridge CB2 1LQ, UK
Can dendrites read out spatiotemporal input sequences? Combining two-photon glutamate uncaging and two-photon calcium imaging, electrophysiology, and computational modeling, Branco et al. (see the Perspective by Destexhe) discovered that single dendrites were indeed sensitive to both the direction and velocity of synaptic inputs. This direction and velocity sensitivity was measurable with only a few inputs and should thus be engaged frequently during normal brain function.
Citation: P. R. Stern, Discriminating Dendrites. Sci. Signal. 3, ec302 (2010).
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