Sci. Signal., 5 October 2010
Science Signaling Podcast: 5 October 2010
Dirk M. Hermann1 and Annalisa M. VanHook2
1 Department of Neurology, University Hospital Essen, Germany.
Abstract: This is a conversation with Dirk Hermann about a Research Article published in the 5 October 2010 issue of Science Signaling. ElAli and Hermann report that apolipoprotein E (ApoE) regulates ATP-binding cassette (ABC) drug transporters in the ischemic brain, thereby controlling brain-to-blood drug distribution. Inhibition of ApoE signaling is a potential clinical strategy for enhancing the delivery of neuroprotective drugs to the brain after ischemic stroke.
Citation: D. M. Hermann, A. M. VanHook, Science Signaling Podcast: 5 October 2010. Sci. Signal. 3, pc18 (2010).
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