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Sci. Signal., 5 October 2010
Vol. 3, Issue 142, p. pe35
[DOI: 10.1126/scisignal.3142pe35]


Mechanisms of Sperm-Egg Interactions: Between Sugars and Broken Bonds

Pablo E. Visconti1* and Harvey M. Florman2*

1 Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA.
2 Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

Abstract: A model of the early events of mammalian fertilization has emerged during the past 30 years. However, studies during the past decade have used newly available mouse models to readdress these processes. Here, we will consider these new data in light of the existing model and point to areas of reconciliation and of controversy.

* Corresponding authors. Telephone, 413-545-5565; fax, (413) 545-6326; e-mail, pvisconti{at} (P.E.V.). Telephone, 508-856-1675; fax, (508) 856-1033; e-mail, harvey.florman{at} (H.M.F.)

Citation: P. E. Visconti, H. M. Florman, Mechanisms of Sperm-Egg Interactions: Between Sugars and Broken Bonds. Sci. Signal. 3, pe35 (2010).

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