Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Subscribe

Sci. Signal., 16 November 2010
Vol. 3, Issue 148, p. ec352
[DOI: 10.1126/scisignal.3148ec352]

EDITORS' CHOICE

Cardiac Physiology A Steady Beat

Pamela J. Hines

Science, AAAS, Washington, DC 20005, USA

A regular heartbeat depends on steady function of the cardiac pacemaker. The early embryonic heart is neither as steady nor as organized as the mature heart. Arrenberg et al. used zebrafish engineered to express light-sensitive proteins to locate and manipulate the function of the cardiac pacemaker. By controlling the activity of small patches of cells with light beams, the authors monitored the development of the young heart, showing how the cardiac pacemaker develops during embryogenesis.

A. B. Arrenberg, D. Y. R. Stainier, H. Baier, J. Huisken, Optogenetic control of cardiac function. Science 330, 971–974 (2010). [Abstract] [Full Text]

Citation: P. J. Hines, A Steady Beat. Sci. Signal. 3, ec352 (2010).



To Advertise     Find Products


Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882