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Sci. Signal., 7 December 2010
Vol. 3, Issue 151, p. eg12
[DOI: 10.1126/scisignal.3151eg12]


Focus Issue: Metabolic Signals

Wei Wong1*

1 Associate Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.

Abstract: This Focus Issue of Science Signaling complements the Science Special Issue on Metabolism ( by turning attention to the pathways and molecules involved in controlling cellular metabolic processes. Highlights include an unexpected role in triggering apoptosis for the insulin receptor and the related IGF-1 receptor (known for their roles in metabolism and growth), a role for lipids as cellular sensors of glucose metabolism, and a mechanism whereby cells can survive oxidative stress by shifting the activity of the cell’s protein degradation complex.

* Corresponding author. E-mail, wwong{at}

Citation: W. Wong, Focus Issue: Metabolic Signals. Sci. Signal. 3, eg12 (2010).

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882