Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Sci. Signal., 29 March 2011
Vol. 4, Issue 166, p. eg3
Focus Issue: Rendering Resistance Futile
Elizabeth M. Adler1* and
Nancy R. Gough2
1 Senior Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA. 2 Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.
In conjunction with the Science special issue on cancer (http://www.sciencemag.org/special/cancer2011/), this issue of Science Signaling focuses on mechanisms whereby cancer cells become resistant to antineoplastic therapy. This issue explores mechanisms whereby cancer cells can become resistant to classical chemotherapy drugs aimed at rapidly proliferating cells or to newer agents that depend on specific inhibition of oncogenic kinases or downstream components of aberrantly activated signaling pathways.
Daniela Beck, Heike Niessner, Keiran S. M. Smalley, Keith Flaherty, Kim H. T. Paraiso, Christian Busch, Tobias Sinnberg, Sophie Vasseur, Juan Lucio Iovanna, Stefan Drießen, Björn Stork, Sebastian Wesselborg, Martin Schaller, Tilo Biedermann, Jürgen Bauer, Konstantinos Lasithiotakis, Benjamin Weide, Jürgen Eberle, Birgit Schittek, Dirk Schadendorf, Claus Garbe, Dagmar Kulms, and Friedegund Meier (29 January 2013) Sci. Signal.6 (260), ra7.
[DOI: 10.1126/scisignal.2003057] |Editor's Summary »|Abstract »|Full Text »|PDF »|Supplementary Materials »
Wei Wong (4 December 2012) Sci. Signal.5 (253), ec309.
[DOI: 10.1126/scisignal.2003835] |Abstract »
John F. Foley (23 October 2012) Sci. Signal.5 (247), ec274.
[DOI: 10.1126/scisignal.2003713] |Abstract »
Rui Kang and Daolin Tang (23 October 2012) Sci. Signal.5 (247), pe47.
[DOI: 10.1126/scisignal.2003511] |Abstract »|Full Text »|PDF »