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Sci. Signal., 5 April 2011
Vol. 4, Issue 167, p. pc7
[DOI: 10.1126/scisignal.2002027]


Science Signaling Podcast: 5 April 2011

Sophie Ugolini1,2,3, Eric Vivier1,2,3,4, and Annalisa M. VanHook5

1 Centre d’Immunologie de Marseille-Luminy, Université de la Méditerranée, Campus de Luminy case 906, 13288 Marseille, France.
2 INSERM U631, Marseille, France.
3 CNRS, UMR6102, Marseille, France.
4 Assistance Publique – Hôpitaux de Marseille, Hôpital de la Conception, 13385 Marseille, France.
5 Web Editor, Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.

Abstract: This Podcast features a conversation with the senior authors of a Research Article published in the April 5 issue of Science Signaling. Sophie Ugolini and Eric Vivier discuss their team’s finding that signaling through inhibitory NK cell receptors determines the distribution of activating receptors, which, in turn, determines the responsiveness of the cells to activating stimuli. This finding suggests that inhibitory receptors can affect membrane receptor organization and hence the responsiveness of NK cells.

Citation: S. Ugolini, E. Vivier, A. M. VanHook, Science Signaling Podcast: 5 April 2011. Sci. Signal. 4, pc7 (2011).

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882