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Sci. Signal., 22 November 2011
Vol. 4, Issue 200, p. pt8
[DOI: 10.1126/scisignal.2002434]

PRESENTATIONS

Direct Delivery Mechanisms of Morphogen Dispersion

Sougata Roy and Thomas B. Kornberg*

Cardiovascular Research Institute, University of California, San Francisco, CA 94158, USA.

A Presentation from the 1st International HEALING Meeting: Hh-Gli Signaling in Development, Regeneration, and Disease, Kolymbari, Crete, 23 to 25 June 2011.

Abstract: This Presentation focuses on how morphogen signaling proteins disperse across developmental fields. Although the steady-state distributions of morphogen signaling proteins have been described well in a number of contexts, the mechanisms that generate these distributions have remained uncertain. Results presented here show that these proteins transfer from producing to target cells at points of direct contact, even when the producing and target cells are not immediate neighbors.

* Presenter and corresponding author. E-mail: tom.kornberg{at}ucsf.edu

Citation: S. Roy, T. B. Kornberg, Direct Delivery Mechanisms of Morphogen Dispersion. Sci. Signal. 4, pt8 (2011).

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Morphogen transport.
P. Muller, K. W. Rogers, S. R. Yu, M. Brand, and A. F. Schier (2013)
Development 140, 1621-1638
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