Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Sci. Signal., 22 November 2011
Vol. 4, Issue 200, p. pt8
[DOI: 10.1126/scisignal.2002434]


Direct Delivery Mechanisms of Morphogen Dispersion

Sougata Roy and Thomas B. Kornberg*

Cardiovascular Research Institute, University of California, San Francisco, CA 94158, USA.

A Presentation from the 1st International HEALING Meeting: Hh-Gli Signaling in Development, Regeneration, and Disease, Kolymbari, Crete, 23 to 25 June 2011.

Abstract: This Presentation focuses on how morphogen signaling proteins disperse across developmental fields. Although the steady-state distributions of morphogen signaling proteins have been described well in a number of contexts, the mechanisms that generate these distributions have remained uncertain. Results presented here show that these proteins transfer from producing to target cells at points of direct contact, even when the producing and target cells are not immediate neighbors.

* Presenter and corresponding author. E-mail: tom.kornberg{at}

Citation: S. Roy, T. B. Kornberg, Direct Delivery Mechanisms of Morphogen Dispersion. Sci. Signal. 4, pt8 (2011).

Read the Full Text

Morphogen transport.
P. Muller, K. W. Rogers, S. R. Yu, M. Brand, and A. F. Schier (2013)
Development 140, 1621-1638
   Abstract »    Full Text »    PDF »

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882