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Sci. Signal., 10 January 2012
Vol. 5, Issue 206, p. eg2
[DOI: 10.1126/scisignal.2002806]
EDITORIAL GUIDES
Focus Issue: Wnt and β-Catenin Signaling in Development and Disease
Nancy R. Gough*
Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.
Abstract:
The Wnt pathways represent key signaling networks involved in development, both in tissue specification and in cellular migration. Wnt signaling also plays key roles in tissue homeostasis in adult animals, and aberrant Wnt signaling is associated with several forms of cancer. This issue includes descriptions of a proapoptotic function for Wnt signaling in melanoma, an interplay between Wnt and bone morphogenetic proteins in tooth organogenesis, and a noncanonical role for Wnt in neuronal guidance.
The editors suggest the following Related Resources on Science sites:
In Science Signaling
RESEARCH ARTICLES
Allie H. Grossmann, Jae Hyuk Yoo, James Clancy, Lise K. Sorensen, Alanna Sedgwick, Zongzhong Tong, Kirill Ostanin, Aaron Rogers, Kenneth F. Grossmann, Sheryl R. Tripp, Kirk R. Thomas, Crislyn D’Souza-Schorey, Shannon J. Odelberg, and Dean Y. Li (5 March 2013) Sci. Signal.6 (265), ra14.
[DOI: 10.1126/scisignal.2003398] |Editor's Summary »|Abstract »|Full Text »|PDF »|Supplementary Materials »
EDITORS' CHOICE
L. Bryan Ray (11 December 2012) Sci. Signal.5 (254), ec319.
[DOI: 10.1126/scisignal.2003850] |Abstract »
MEETING REPORTS
Folkert Verkaar, Ken M. Cadigan, and Renée van Amerongen (11 December 2012) Sci. Signal.5 (254), mr2.
[DOI: 10.1126/scisignal.2003714] |Abstract »|Full Text »|PDF »
EDITORS' CHOICE
Valda K. Vinson (10 July 2012) Sci. Signal.5 (232), ec187.
[DOI: 10.1126/scisignal.2003373] |Abstract »
PODCASTS
K. Christopher Garcia and Annalisa M. VanHook (3 July 2012) Sci. Signal.5 (231), pc15.
[DOI: 10.1126/scisignal.2003307] |Abstract »|Full Text »|Podcast »
EDITORS' CHOICE
Nancy R. Gough (12 June 2012) Sci. Signal.5 (228), ec162.
[DOI: 10.1126/scisignal.2003300] |Abstract »
PERSPECTIVES
Ju Bao, Jie J. Zheng, and Dianqing Wu (15 May 2012) Sci. Signal.5 (224), pe22.
[DOI: 10.1126/scisignal.2003028] |Abstract »|Full Text »|PDF »
EDITORS' CHOICE
John F. Foley (17 April 2012) Sci. Signal.5 (220), ec113.
[DOI: 10.1126/scisignal.2003141] |Abstract »
RESEARCH ARTICLES
Travis L. Biechele, Rima M. Kulikauskas, Rachel A. Toroni, Olivia M. Lucero, Reyna D. Swift, Richard G. James, Nick C. Robin, David W. Dawson, Randall T. Moon, and Andy J. Chien (10 January 2012) Sci. Signal.5 (206), ra3.
[DOI: 10.1126/scisignal.2002274] |Editor's Summary »|Abstract »|Full Text »|PDF »|Supplementary Materials »
RESEARCH ARTICLES
Daniel J. O’Connell, Joshua W. K. Ho, Tadanori Mammoto, Annick Turbe-Doan, Joyce T. O’Connell, Psalm S. Haseley, Samuel Koo, Nobuhiro Kamiya, Donald E. Ingber, Peter J. Park, and Richard L. Maas (10 January 2012) Sci. Signal.5 (206), ra4.
[DOI: 10.1126/scisignal.2002414] |Editor's Summary »|Abstract »|Full Text »|PDF »|Supplementary Materials »
PROTOCOLS
Katrin Luckert, Taranjit S. Gujral, Marina Chan, Mark Sevecka, Thomas O. Joos, Peter K. Sorger, Gavin MacBeath, and Oliver Pötz (10 January 2012) Sci. Signal.5 (206), pl1.
[DOI: 10.1126/scisignal.2002372] |Abstract »|Full Text »|PDF »
PRESENTATIONS
B. Ian Hutchins, Li Li, and Katherine Kalil (10 January 2012) Sci. Signal.5 (206), pt1.
[DOI: 10.1126/scisignal.2002523] |Abstract »|Full Text »|PDF »|Slideshow »
