Sci. Signal., 20 March 2012
Neuroscience A Synaptic Vesicle in Time
Stella M. Hurtley
Science, AAAS, Cambridge CB2 1LQ, UK
Synaptic vesicles move extensively within presynaptic nerve terminals, and their positional features are thought to have an impact on the likelihood and mode of vesicle fusion and transmitter release. Park et al. now provide real-time, three-dimensional tracking of individual synaptic vesicles in living nerve terminals. Single synaptic vesicles were identified within hippocampal neurons right up to the moment of exocytosis.
Citation: S. M. Hurtley, A Synaptic Vesicle in Time. Sci. Signal. 5, ec88 (2012).
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