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Sci. Signal., 29 May 2012
Vol. 5, Issue 226, p. eg7
[DOI: 10.1126/scisignal.2003235]

EDITORIAL GUIDES

Focus Issue: Signaling Architecture from Domains to Complexes

Wei Wong1* and Nancy R. Gough2

1 Associate Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.
2 Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.

Abstract: Science Signaling concludes a series on structural biology, which has focused on the use of structural approaches to understand signal transduction. Articles in this issue highlight the importance of the helical domain in Gα proteins, discuss how linear peptide motifs are recognized by a protein domain, and describe the assembly of macromolecular complexes upon activation of Toll-like and interleukin-1 receptors.

* Corresponding author. E-mail: wwong{at}aaas.org

Citation: W. Wong, N. R. Gough, Focus Issue: Signaling Architecture from Domains to Complexes. Sci. Signal. 5, eg7 (2012).

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