Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Logo for

PNAS 99 (4): 2428-2432

Copyright © 2002 by the National Academy of Sciences.


Crosstalk among stress responses in plants: Pathogen defense overrides UV protection through an inversely regulated ACE/ACE type of light-responsive gene promoter unit

Elke Logemann Klaus Hahlbrock*

Max Planck Institute for Plant Breeding Research, Carl-von-Linné-Weg 10, D-50829 Köln, Germany

Contributed by Klaus Hahlbrock

Accepted for publication December 21, 2001.

Abstract: Plants often have to cope with two or more environmental hazards simultaneously. Such coincidences require instantaneous decisions on relative severity and consequential crosstalk between the respective signaling cascades. Among the frequently encountered threats are pathogen infections and UV irradiation, both of which trigger specifically targeted defense responses by means of changes in gene transcription rates. In Petroselinum crispum, pathogen defense has been shown to be associated with extensive metabolic reprogramming, including strong repression of the UV-protective flavonoid biosynthetic pathway. Here we show that one of the involved genes, encoding acyl-CoA oxidase, responds positively to UV light and negatively to a pathogen-derived elicitor through an inversely regulated promoter unit consisting of two almost identical ACGT-containing elements (ACEs). This unit, when either introduced into an unrelated promoter or generated by mutation of a differently composed unit, confers the same type of response pattern on the recipient genes, confirming its general functionality at a convergence site of two largely distinct signaling pathways. Similarly large, rapid, and partly inverse effects of UV light and elicitor were observed for several mRNAs encoding common plant regulatory factors (CPRFs) that exhibit distinct dimerization and DNA-binding properties. This striking coincidence suggests a major role of common plant regulatory factors in mediating the apparent switch in the function of ACGT-containing elements from positive UV light to negative elicitor or pathogen responsiveness.

* To whom reprint requests should be addressed. E-mail: hahlbroc{at}

Repression of Sucrose/Ultraviolet B Light-Induced Flavonoid Accumulation in Microbe-Associated Molecular Pattern-Triggered Immunity in Arabidopsis.
M. Serrano, K. Kanehara, M. Torres, K. Yamada, N. Tintor, E. Kombrink, P. Schulze-Lefert, and Y. Saijo (2012)
Plant Physiology 158, 408-422
   Abstract »    Full Text »    PDF »
Cis-regulatory Evolution of Chalcone-Synthase Expression in the Genus Arabidopsis.
J. de Meaux, A. Pop, and T. Mitchell-Olds (2006)
Genetics 174, 2181-2202
   Abstract »    Full Text »    PDF »
Comparative cDNA-AFLP analysis of Cd-tolerant and -sensitive genotypes derived from crosses between the Cd hyperaccumulator Arabidopsis halleri and Arabidopsis lyrata ssp. petraea.
A. R. Craciun, M. Courbot, F. Bourgis, P. Salis, P. Saumitou-Laprade, and N. Verbruggen (2006)
J. Exp. Bot. 57, 2967-2983
   Abstract »    Full Text »    PDF »
Structural Complexity, Differential Response to Infection, and Tissue Specificity of Indolic and Phenylpropanoid Secondary Metabolism in Arabidopsis Roots.
P. Bednarek, B. Schneider, A. Svatos, N. J. Oldham, and K. Hahlbrock (2005)
Plant Physiology 138, 1058-1070
   Abstract »    Full Text »    PDF »
Allele-Specific Assay Reveals Functional Variation in the Chalcone Synthase Promoter of Arabidopsis thaliana That Is Compatible with Neutral Evolution.
J. de Meaux, U. Goebel, A. Pop, and T. Mitchell-Olds (2005)
PLANT CELL 17, 676-690
   Abstract »    Full Text »    PDF »
Ultraviolet-B Radiation-Mediated Responses in Plants. Balancing Damage and Protection.
H. Frohnmeyer and D. Staiger (2003)
Plant Physiology 133, 1420-1428
   Full Text »
Pathogen-Responsive Expression of a Putative ATP-Binding Cassette Transporter Gene Conferring Resistance to the Diterpenoid Sclareol Is Regulated by Multiple Defense Signaling Pathways in Arabidopsis.
E. J. Campbell, P. M. Schenk, K. Kazan, I. A.M.A. Penninckx, J. P. Anderson, D. J. Maclean, B. P.A. Cammue, P. R. Ebert, and J. M. Manners (2003)
Plant Physiology 133, 1272-1284
   Abstract »    Full Text »    PDF »
Arabidopsis Mutants in Short- and Medium-chain Acyl-CoA Oxidase Activities Accumulate Acyl-CoAs and Reveal That Fatty Acid {beta}-Oxidation Is Essential for Embryo Development.
E. L. Rylott, C. A. Rogers, A. D. Gilday, T. Edgell, T. R. Larson, and I. A Graham (2003)
J. Biol. Chem. 278, 21370-21377
   Abstract »    Full Text »    PDF »

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882