Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Logo for

Science 338 (6112): 1303-1304

Copyright © 2012 by the American Association for the Advancement of Science

Inflammation to Rebuild a Brain

Nephi Stella

Department of Pharmacology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA.

Figure 1
View larger version (38K):
[in this window]
[in a new window]

Brain regeneration. In the zebrafish brain, injured neurons release a signal (LTC4) that stimulates resident immune cells (microglia, leukocytes, and other glia) to release a signal (LTC4) that promotes neurogenesis. The transcription factor Gata3 in both the immune cells and the neuronal progenitor cells may operate as a molecular switch that controls the repair phenotype of the inflammation.



To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882