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Science 339 (6116): 152-153

Copyright © 2013 by the American Association for the Advancement of Science

Developmental Refining of Neuroglial Signaling?

Antje Grosche, and Andreas Reichenbach

Paul Flechsig Institute of Brain Research, Leipzig University, Jahnallee 59, 04109 Leipzig, Germany.

Figure 1
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Tripartite synapses, maturing. A schematic hypothetical survey of mGluR5-mediated calcium (Ca) rises and gliotransmitter release in multicellular glial networks during brain maturation (left) versus local responses in glial microdomains of the mature brain (right). These changes may be reversible after injury. Neurons are shown in gray.



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