Sci. Signal., 14 February 2012
Measurement of cAMP in an Undergraduate Teaching Laboratory, Using ALPHAscreen Technology
Joseph D. Bartho, Kien Ly, Debbie L. Hay*
School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Presentation. Signal Transduction in Drug Discovery.
This presentation was used in conjunction with the laboratory exercise for a class of >300 second-year biochemistry students. In addition to describing the lab and providing tips for the students for execution of the laboratory procedures, the presentation includes an overview of the drug discovery process, the use of technologies such as ALPHAscreen in drug discovery, and their advantages over conventional techniques. It also briefly highlights G protein–coupled receptors as therapeutic targets and discusses methods for detecting the intracellular signaling messenger cyclic adenosine monophosphate (cAMP).
Size: 1.27 MB
Requirements: Adobe Acrobat Reader
Learning Resource Type: Digital Presentation
Citation: J. D. Bartho, K. Ly, D. L. Hay, Measurement of cAMP in an undergraduate teaching laboratory, using ALPHAscreen technology. Sci. Signal. 5, tr1 (2012).
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