Supplementary Materials for:
Mitochondrial Reactive Oxygen Species Promote Epidermal
Differentiation and Hair Follicle Development
Robert B. Hamanaka, Andrea Glasauer, Paul Hoover, Shuangni Yang, Hanz Blatt,
Andrew R. Mullen, Spiro Getsios, Cara J. Gottardi, Ralph J. DeBerardinis,
Robert M. Lavker, Navdeep S. Chandel*
*To whom correspondence should be addressed. E-mail: nav{at}northwestern.edu
This PDF file includes:
- Fig. S1. Analysis of epidermal apoptosis and epidermal thickness in control and
TFAM cKO skin.
- Fig. S2. Sensitivity of control keratinocyte differentiation to exogenous H2O2 and
inhibition of mitochondrial calcium uptake.
- Fig. S3. Analysis of cellular signaling pathways in control and TFAM cKO
keratinocytes.
- Fig. S4. Sensitivity of Notch signaling to ROS during keratinocyte differentiation.
- Fig. S5. Sensitivity of Wnt–β-catenin signaling to ROS in epidermal keratinocytes.
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Citation: R. B. Hamanaka, A. Glasauer, P. Hoover, S. Yang, H. Blatt, A. R. Mullen, S. Getsios,
C. J. Gottardi, R. J. DeBerardinis, R. M. Lavker, N. S. Chandel, Mitochondrial Reactive Oxygen Species Promote Epidermal
Differentiation and Hair Follicle Development.
Sci. Signal. 6, ra8 (2013).
© 2013 American Association for the Advancement of Science