Differential p53-Independent Outcomes of p19^Arf Loss in Oncogenesis

Zhenbang Chen, Arkaitz Carracedo, Hui-Kuan Lin, Jason A. Koutcher, Nille Behrendt, Ainara Egia, Andrea Alimonti, Brett S. Carver, William Gerald, Julie Teruya-Feldstein, Massimo Loda, Pier Paolo Pandolfi*

*To whom correspondence should be addressed. E-mail: ppandolf{at}bidmc.harvard.edu

This PDF file includes:

• Fig. S1. Generation of p19^Arf–/–;Ptenpc^–/– mice and visualization of prostate tumors.
• Fig. S2. Immunohistochemical analysis of p21 in mouse prostate.
• Fig. S3. In vitro characterization of p19^Arf–/–-Pten^Δ/Δ double-null MEFs.
• Fig. S4. Lack of correlation between p53 and p14^ARF expression in human prostate cancer biopsies.
• Fig. S5. Nucleophosmin abundance and localization in MEFs.

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Citation: Z. Chen, A. Carracedo, H.-K. Lin, J. A. Koutcher, N. Behrendt, A. Egia, A. Alimonti, B. S. Carver, W. Gerald, J. Teruya-Feldstein, M. Loda, P. P. Pandolfi, Differential p53-independent outcomes of p19^Arf loss in oncogenesis. Sci. Signal. 2, ra44 (2009).

© 2009 American Association for the Advancement of Science