Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Sci. Signal., 29 September 2009
[DOI: 10.1126/scisignal.2000300]

Supplementary Materials for:

Hippo Pathway–Dependent and –Independent Roles of RASSF6

Mitsunobu Ikeda, Akira Kawata, Misa Nishikawa, Yuko Tateishi, Masato Yamaguchi, Kentaro Nakagawa, Susumu Hirabayashi, Yijun Bao, Shiho Hidaka, Yukio Hirata, Yutaka Hata*

*To whom correspondence should be addressed. E-mail: yuhammch{at}tmd.ac.jp

This PDF file includes:

  • Fig. S1. Interaction of RASSF6 with MST2.
  • Fig. S2. Molecular determinants of the interaction of MST2 with RASSF6 and WW45.
  • Fig. S3. OA treatment induces apoptosis in rat hepatocytes.
  • Fig. S4. The effect of the expression of various MST2 and WW45 proteins.
  • Fig. S5. MST1 inhibits RASSF6-induced apoptosis, whereas RASSF6 inhibits the phosphorylation of MOB1 by MST1.
  • Fig. S6. RASSF6-induced apoptosis is independent of the interaction with MST2 and NDR kinases.
  • Fig. S7. Interaction of MOAP1 with RASSF6 and dRASSF.
  • Fig. S8. dRASSF interacts with and inhibits MST2.
  • Fig. S9. dRASSF or RASSF6 does not induce apoptosis in S2 cells.
  • Table S1. Twenty-one–nucleotide oligomers used in this study.
  • Table S2. Primers for quantitative RT-PCR.

[Download PDF]

Technical Details

Format: Adobe Acrobat PDF

Size: 2.29 MB


Citation: M. Ikeda, A. Kawata, M. Nishikawa, Y. Tateishi, M. Yamaguchi, K. Nakagawa, S. Hirabayashi, Y. Bao, S. Hidaka, Y. Hirata, Y. Hata, Hippo Pathway–Dependent and –Independent Roles of RASSF6. Sci. Signal. 2, ra59 (2009).

© 2009 American Association for the Advancement of Science


To Advertise     Find Products


Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882