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Sci. STKE, 25 April 2000
[DOI: 10.1126/stke.2000.29.pe1]

Trans-endocytosis of Notch Movie

This movie shows how trans-endocytosis of Notch into Delta expressing cells contributes to Notch activation. N-ECD represents the Notch extracellular domain, N-ICD represents Notch intracellular domain, {delta} represents the Delta ligand. Animation created by BioCreations.

After clicking on the "Start" button at the bottom right of the movie screen, please click on the subsequent left or right arrows to go backward or forward in the movie.

Citation: H. Krämer, RIPping Notch Apart: A New Role for Endocytosis in Signal Transduction? Science's STKE (2000), http://stke.sciencemag.org/cgi/content/full/sigtrans;2000/29/pe1


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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882