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Sci. STKE, 11 December 2001
[DOI: 10.1126/stke.2001.112.re20]

Movie 2. Inhibition of stimulated Eph-A3 receptors Movie

Following stimulation of HEK 293T cells expressing pEGFP actin and Eph A3, nonclustered ephrin-A5 ligand is added to the cells and acts as a competitive inhibitor (1). Cells start to ruffle. Total length of sequence (frame interval optional): 60 min, 1 frame min-1. Frame width, 90 µm. From: I. Lawrenson, S. H. Cody, M. Lackmann, Morphological changes following Eph receptor stimulation. Trends in Cell Biology 11, CD-ROM Supplement, GFP in Motion 2, 2001. Copyright: Contributors retain the copyright for the data provided and are allowed to use it for peer-reviewed research reports without requesting consent from the publisher of GFP in Motion 2.

Citation: A. W. Boyd, M. Lackmann, Signals from Eph and Ephrin Proteins: A Developmental Tool Kit. Science's STKE (2001), http://stke.sciencemag.org/cgi/content/full/OC_sigtrans;2001/112/re20.


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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882