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Sci. Signal., 5 January 2010
[DOI: 10.1126/scisignal.2000551]

Supplementary Materials for:

Impaired αIIbβ3 Integrin Activation and Shear-Dependent Thrombus Formation in Mice Lacking Phospholipase D1

Margitta Elvers, David Stegner, Ina Hagedorn, Christoph Kleinschnitz, Attila Braun, Marijke E. J. Kuijpers, Michael Boesl, Qin Chen, Johan W. M. Heemskerk, Guido Stoll, Michael A. Frohman, Bernhard Nieswandt*

*To whom correspondence should be addressed. E-mail: bernhard.nieswandt{at}virchow.uni-wuerzburg.de

This PDF file includes:

  • Table S1. Blood cell counts and platelet glycoprotein expression of Pld1−/− mice.
  • Fig. S1. Generation of PLD1-deficient mice.
  • Fig. S2. Impaired αIIbβ3 activation in Pld1−/− platelets under stirring conditions.
  • Fig. S3. Botrocetin induces vWF binding, but not integrin activation, in platelets.

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Format: Adobe Acrobat PDF

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Citation: M. Elvers, D. Stegner, I. Hagedorn, C. Kleinschnitz, A. Braun, M. E. J. Kuijpers, M. Boesl, Q. Chen, J. W. M. Heemskerk, G. Stoll, M. A. Frohman, B. Nieswandt, Impaired αIIbβ3 Integrin Activation and Shear-Dependent Thrombus Formation in Mice Lacking Phospholipase D1. Sci. Signal. 3, ra1 (2010).

© 2010 American Association for the Advancement of Science

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