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Sci. Signal., 9 February 2010
[DOI: 10.1126/scisignal.2000628]

Supplementary Materials for:

SUMOylation Mediates the Nuclear Translocation and Signaling of the IGF-1 Receptor

Bita Sehat, Ali Tofigh, Yingbo Lin, Eric Trocmé, Ulrika Liljedahl, Jens Lagergren, Olle Larsson*

*To whom correspondence should be addressed. E-mail: Olle.Larsson{at}ki.se

This PDF file includes:

  • Materials and Methods
  • Fig. S1. Further characterization of the SUMOylation and nuclear accumulation of IGF-1R.
  • Fig. S2. SUMO-1 binding site requirement and DNA binding of nIGF-1R.
  • Table S1. Sequences of the randomly synthesized double-stranded DNA fragments that were used for EMSAs.
  • Table S2. Sequences of the DNA fragments that were bound to IGF-1R.
  • Table S3. Features of the ChIP sequences.
  • Table S4. Sequences of the primers used to construct reporter plasmids.
  • Table S5. Sequences of the primers used to construct IGF-1R mutants.
  • References

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Technical Details

Format: Adobe Acrobat PDF

Size: 1.5 MB


Citation: B. Sehat, A. Tofigh, Y. Lin, E.Trocmé, U. Liljedahl, J. Lagergren, O. Larsson, SUMOylation Mediates the Nuclear Translocation and Signaling of the IGF-1 Receptor. Sci. Signal. 3, ra10 (2010).

© 2010 American Association for the Advancement of Science


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