Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Sci. Signal., 29 June 2010
[DOI: 10.1126/scisignal.2000803]

Supplementary Materials for:

Evolution of the TSC1/TSC2-TOR Signaling Pathway

Jaco Serfontein, R. Ellen R. Nisbet, Christopher J. Howe,* Petrus J. de Vries

*To whom correspondence should be addressed. E-mail: c.j.howe{at}

This PDF file includes:

  • Supplementary Text. List of inferred protein sequences searched using HMMER, and homologs found using BLAST, PSI-BLAST or HMMER.
  • Fig. S1. Alignment of part of TSC2 sequences.
  • Fig. S2. Alignment of part of TSC1 sequences.

[Download PDF]

Technical Details

Format: Adobe Acrobat PDF

Size: 118 KB

Citation: J. Serfontein, R. E. R. Nisbet, C. J. Howe, P. J. de Vries, Evolution of the TSC1/TSC2-TOR Signaling Pathway. Sci. Signal. 3, ra49 (2010).

© 2010 American Association for the Advancement of Science

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882