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Sci. Signal., 23 November 2010
[DOI: 10.1126/scisignal.2001158]

Supplementary Materials for:

HLA Class I Molecules Partner with Integrin β4 to Stimulate Endothelial Cell Proliferation and Migration

Xiaohai Zhang, Enrique Rozengurt, Elaine F. Reed*

*To whom correspondence should be addressed. E-mail: ereed{at}mednet.ucla.edu

This PDF file includes:

  • Fig. S1. Immunoprecipitation with an integrin β1–specific antibody fails to pull down integrin β4 and the HLA-I heavy chain in endothelial cells.
  • Fig. S2. Knockdown of integrin β4 blocks HLA-I–mediated phosphorylation of target proteins in endothelial cells.
  • Fig. S3. The cytoplasmic domain of the HLA-I heavy chain is required for HLA-I–mediated cell proliferation.
  • Fig. S4. Knockdown of the HLA-I heavy chain inhibits the phosphorylation of ERK.

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Citation: X. Zhang, E. Rozengurt, E. F. Reed, HLA Class I Molecules Partner with Integrin β4 to Stimulate Endothelial Cell Proliferation and Migration. Sci. Signal. 3, ra85 (2010).

© 2010 American Association for the Advancement of Science


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