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Sci. Signal., 15 March 2011
[DOI: 10.1126/scisignal.2001464]

Supplementary Materials for:

LRP6 Mediates cAMP Generation by G Protein–Coupled Receptors Through Regulating the Membrane Targeting of Gαs

Mei Wan,* Jun Li, Katie Herbst, Jin Zhang, Bing Yu, Xiangwei Wu, Tao Qiu, Weiqi Lei, Charlotta Lindvall, Bart O. Williams, Hairong Ma, Fengjie Zhang, Xu Cao*

*To whom correspondence should be addressed. E-mail: mwan4{at}jhmi.edu (M.W.); xcao11{at}jhmi.edu (X.C.)

This PDF file includes:

  • Fig. S1. Mass spectrometric identification of a PKA phosphorylation site in LRP6.
  • Fig. S2. Identification of the Gαs interaction domain in LRP6.

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Technical Details

Format: Adobe Acrobat PDF

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Citation: M. Wan, J. Li, K. Herbst, J. Zhang, B. Yu, X. Wu, T. Qiu, W. Lei, C. Lindvall, B. O. Williams, H. Ma, F. Zhang, X. Cao, LRP6 Mediates cAMP Generation by G Protein–Coupled Receptors Through Regulating the Membrane Targeting of Gαs. Sci. Signal. 4, ra15 (2011).

© 2011 American Association for the Advancement of Science


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