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Sci. Signal., 1 November 2011
[DOI: 10.1126/scisignal.2001843]

Supplementary Materials for:

A CC′ Loop Decoy Peptide Blocks the Interaction Between Act1 and IL-17RA to Attenuate IL-17– and IL-25–Induced Inflammation

Caini Liu, Shadi Swaidani, Wen Qian, Zizhen Kang, Paige Sun, Yue Han, Chenhui Wang, Muhammet Fatih Gulen, Weiguo Yin, Chunjiang Zhang, Paul L. Fox, Mark Aronica, Thomas A. Hamilton, Saurav Misra, Junpeng Deng, Xiaoxia Li*

*To whom correspondence should be addressed. E-mail: lix{at}ccf.org

This PDF file includes:

  • Fig. S1. A cell-permeable CC′ loop decoy peptide inhibits IL-17– and IL-25–dependent gene expression in a dose- and time-dependent manner.
  • Fig. S2. A cell-permeable CC′ loop decoy peptide inhibits IL-17– and IL-25–induced pulmonary inflammation in mice in a dose-dependent manner.
  • Table S1. SEFIR domain homology modeling data.

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Technical Details

Format: Adobe Acrobat PDF

Size: 160 KB


Citation: C. Liu, S. Swaidani, W. Qian, Z. Kang, P. Sun, Y. Han, C. Wang, M. F. Gulen, W. Yin, C. Zhang, P. L. Fox, M. Aronica, T. A. Hamilton, S. Misra, J. Deng, X. Li, A CC′ Loop Decoy Peptide Blocks the Interaction Between Act1 and IL-17RA to Attenuate IL-17– and IL-25–Induced Inflammation. Sci. Signal. 4, ra72 (2011).

© 2011 American Association for the Advancement of Science


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