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Sci. Signal., 7 February 2012
[DOI: 10.1126/scisignal.2002448]

Supplementary Materials for:

PTEN Directly Activates the Actin Depolymerization Factor Cofilin-1 During PGE2-Mediated Inhibition of Phagocytosis of Fungi

C. Henrique Serezani, Steve Kane, Alexandra I. Medeiros, Ashley M. Cornett, Sang-Hoon Kim, Mariana Morato Marques, Sang-Pyo Lee, Casey Lewis, Emilie Bourdonnay, Megan N. Ballinger, Eric S. White, Marc Peters-Golden*

*To whom correspondence should be addressed. E-mail: petersm{at}umich.edu

This PDF file includes:

  • Fig. S1. Actin depolymerizing factors in alveolar macrophages.
  • Fig. S2. Pharmacological inhibition of PTEN prevents the effects of PGE2 on C. albicans phagocytosis.
  • Fig. S3. Individual PTEN siRNAs prevent inhibition of phagocytosis and activation of cofilin-1 by PGE2.

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Technical Details

Format: Adobe Acrobat PDF

Size: 227 KB

Citation: C. H. Serezani, S. Kane, A. I. Medeiros, A. M. Cornett, S.-H. Kim, M. M. Marques, S.-P. Lee, C. Lewis, E. Bourdonnay, M. N. Ballinger, E. S. White, M. Peters-Golden, PTEN Directly Activates the Actin Depolymerization Factor Cofilin-1 During PGE2-Mediated Inhibition of Phagocytosis of Fungi. Sci. Signal. 5, ra12 (2012).

© 2012 American Association for the Advancement of Science

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