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Sci. Signal., 12 June 2012
[DOI: 10.1126/scisignal.2002437]

Supplementary Materials for:

The lin-4 MicroRNA Targets the LIN-14 Transcription Factor to Inhibit Netrin-Mediated Axon Attraction

Yan Zou, Hui Chiu, Dorothée Domenger, Chiou-Fen Chuang,* Chieh Chang*

*To whom correspondence should be addressed. E-mail: chieh.chang{at}cchmc.org (C.C.); chiou-fen.chuang{at}cchmc.org (C.-F.C.)

This PDF file includes:

  • Fig. S1. Global survey of microRNA presence and abundance during C. elegans development.
  • Fig. S2. Responsiveness of a lin-14 3'UTR reporter to ectopic expression of lin-4 microRNA in AVM neurons.
  • Fig. S3. Responsiveness of a lin-14 3'UTR reporter to ectopic expression of miR-125a in AVM neurons.
  • Fig. S4. lin-4 and lin-14 mutations do not affect the timing of AVM axon outgrowth.
  • Fig. S5. The effect of the LIN-14 transcription factor on activity of the promoters of various unc-40 pathway genes in AVM neurons.
  • Table S1. lin-4 mutation does not affect AVM cell fate.
  • Table S2. C. elegans strains used in this study.
  • Table S3. Stem-loop RT primers and forward PCR primers.

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Citation: Y. Zou, H. Chiu, D. Domenger, C.-F. Chuang, C. Chang, The lin-4 MicroRNA Targets the LIN-14 Transcription Factor to Inhibit Netrin-Mediated Axon Attraction. Sci. Signal. 5, ra43 (2012).

© 2012 American Association for the Advancement of Science


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