Supplementary Materials for:
Nucleolar Localization of a Netrin-1 Isoform Enhances Tumor Cell
Proliferation
Céline Delloye-Bourgeois, David Goldschneider, Andrea Paradisi, Gabriel Therizols,
Stéphane Belin, Sabine Hacot, Manuel Rosa-Calatrava, Jean-Yves Scoazec, Jean-Jacques
Diaz, Agnès Bernet, Patrick Mehlen*
*To whom correspondence should be addressed. E-mail: patrick.mehlen{at}lyon.unicancer.fr
This PDF file includes:
- Fig. S1. Depletion of ΔN-netrin-1 affects B23 localization within the nucleolus in
IMR32 cells.
- Fig. S2. Depletion of ΔN-netrin-1 affects B23 localization in the nucleolus in H358
cells.
- Fig. S3. Netrin-1 colocalizes with B23 and nucleolin in the nucleolus.
- Fig. S4. Characterization of the netrin-1 alternative promoter and ΔN-netrin-1.
- Fig. S5. ΔN-netrin-1 specifically associates with ribosomal DNA.
- Fig. S6. ΔN-netrin-1 promotes ribosome biogenesis.
- Fig. S7. Nucleolar ΔN-netrin-1 promotes cell proliferation.
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Citation: C. Delloye-Bourgeois, D. Goldschneider, A. Paradisi, G. Therizols, S. Belin, S. Hacot,
M. Rosa-Calatrava, J.-Y. Scoazec, J.-J. Diaz, A. Bernet, P. Mehlen, Nucleolar Localization of a Netrin-1 Isoform Enhances Tumor Cell
Proliferation.
Sci. Signal. 5, ra57 (2012).
© 2012 American Association for the Advancement of Science