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Sci. Signal., 4 September 2012
[DOI: 10.1126/scisignal.2003253]

Supplementary Materials for:

Guanylyl Cyclases A and B Are Asymmetric Dimers That Are Allosterically Activated by ATP Binding to the Catalytic Domain

Jerid W. Robinson and Lincoln R. Potter*

*To whom correspondence should be addressed. E-mail: potter{at}umn.edu

This PDF file includes:

  • Fig. S1. Detectable amounts of GC-A or GC-B protein are only found in HEK 293T cells specifically transfected with plasmids encoding each receptor.
  • Fig. S2. HEK 293T cells do not have detectable membrane GC activity.
  • Fig. S3. Kinetic values for substrate-velocity experiments presented in the indicated figures.

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Technical Details

Format: Adobe Acrobat PDF

Size: 167 KB


Citation: J. W. Robinson, L. R. Potter, Guanylyl Cyclases A and B Are Asymmetric Dimers That Are Allosterically Activated by ATP Binding to the Catalytic Domain. Sci. Signal. 5, ra65 (2012).

© 2012 American Association for the Advancement of Science


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