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Sci. Signal., 23 April 2013
[DOI: 10.1126/scisignal.2003309]

Supplementary Materials for:

Noncanonical NF-κB Activation by the Oncoprotein Tio Occurs Through a Nonconserved TRAF3-Binding Motif

Sarah Jill de Jong, Jens-Christian Albrecht, Fabian Giehler, Arnd Kieser, Heinrich Sticht, Brigitte Biesinger*

*Corresponding author. E-mail: Brigitte.Biesinger{at}viro.med.uni-erlangen.de

This PDF file includes:

  • Fig. S1. Quantification of the extent of processing of p100 to p52 in the presence of Tio deletion mutants.
  • Fig. S2. Tio does not form complexes with NIK.
  • Fig. S3. Quantification of TRAF3 protein abundance in the presence of Tio.
  • Fig. S4. Tio does not use ubiquitination, lysosomal degradation, or cIAP1 or cIAP2 activity to reduce the abundance of TRAF3.
  • Fig. S5. Quantification of the extent of processing of p100 to p52 in the presence of combinatorial Tio mutants.
  • Table S1. Primer sequences.

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Technical Details

Format: Adobe Acrobat PDF

Size: 1.10 MB


Citation: S. J. de Jong, J.-C. Albrecht, F. Giehler, A. Kieser, H. Sticht, B. Biesinger, Noncanonical NF-κB Activation by the Oncoprotein Tio Occurs Through a Nonconserved TRAF3-Binding Motif. Sci. Signal. 6, ra27 (2013).

© 2013 American Association for the Advancement of Science


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