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Sci. Signal., 17 December 2013
[DOI: 10.1126/scisignal.2004273]

Supplementary Materials for:

Activation of the Transcription Factor c-Maf in T Cells Is Dependent on the CARMA1-IKKβ Signaling Cascade

Marzenna Blonska, Donghyun Joo, Roza I. Nurieva, Xueqiang Zhao, Paul Chiao, Shao-Cong Sun, Chen Dong, Xin Lin*

*Corresponding author. E-mail: xllin{at}mdanderson.org

This PDF file includes:

  • Fig. S1. CARMA- and Bcl10-deficient CD4+ T cells secrete reduced amounts of IL- 21 and CD40L compared to wild-type cells.
  • Fig. S2. The TCR-dependent increase in Maf expression does not require CARMA1.
  • Fig. S3. Generation of Jurkat cell lines stably expressing c-Maf.
  • Fig. S4. Analysis of the efficiency of knockdown of IKKα and IKKβ with different shRNAs.
  • Fig. S5. In vitro kinase assay.
  • Fig. S6. IKKα is not required for the activation of c-Maf or the production of IL-21.

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Citation: M. Blonska, D. Joo, R. I. Nurieva, X. Zhao, P. Chiao, S.-C. Sun, C. Dong, X. Lin, Activation of the Transcription Factor c-Maf in T Cells Is Dependent on the CARMA1-IKKβ Signaling Cascade. Sci. Signal. 6, ra110 (2013).

© 2013 American Association for the Advancement of Science


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