This schematic was prepared by R. Iyengar's laboratory and shows some of the signaling events associated with activation of the b-adrenergic receptor (b-AR), a Gas-coupled receptor. The (b-AR) can regulated gene expression through activation of the transcription factor CREB and can regulate glucose metabolism.
P. Ram, R. Iyengar, Gas Pathway. Sci. STKE (Connections Maps), http://stke.sciencemag.org/cgi/cm/CMP_6634 [Canonical Pathway]
Citation for this schematic: P. Ram, R. Iyengar, An Example of Gs Signaling. Sci. STKE (Supplement to Connections Maps), http://stke.sciencemag.org/cgi/content/full/sigtrans;CMP_6634/DC1
Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882