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A Schematic Showing TNF Signaling.

This schematic was prepared by D. V. Goeddel's laboratory. The diagram illustrates the signaling processes that are initiated by activation of the tumor necrosis factor (TNF) receptor (TNF-R1).

G. Chen, D. V. Goeddel, TNF Pathway. Science's STKE (Connections Maps, as seen May 2002), http://stke.sciencemag.org/cgi/cm/CMP_7107. [Canonical Pathway]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882