This schematic was prepared by R. Iyengar's laboratory and provides an example of the many different signaling modules that can be regulated upon activation of a Gai/o-coupled receptor, the muscarinic acetylcholine receptor (M2R).
R. Iyengar, D. Aaronson, Gai Pathway. Sci. STKE (Connections Maps), http://stke.sciencemag.org/cgi/cm/CMP_7430 [Canonical Pathway]
Citation for this schematic: R. Iyengar, D. Aaronson, An Example of Gi Signaling. Sci. STKE (Supplement to Connections Maps), http://stke.sciencemag.org/cgi/content/full/sigtrans;CMP_7430/DC1
Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882