Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Sci. Signal., 2 September 2008
[DOI: 10.1126/scisignal.1159945]

The Extracellular Calcium-Sensing Receptor (CaSR) Is a Critical Modulator of Skeletal Development

Wenhan Chang,*† Chialing Tu,* Tsui-Hua Chen, Daniel Bikle, Dolores Shoback

Endocrine Research Unit, Department of Veterans Affairs Medical Center, Department of Medicine, University of California, San Francisco, CA 94121, USA.

This PDF file includes:

  • Figure S1. Characterization of the DExon7-CaSR in HEK 293 cells.
  • Figure S2. PCR analysis of control, COL-Het, and COL-KO mice.
  • Figure S3. Histological analysis and gene expression assays of COL-KO mice.
  • Figure S4. PCR analysis of control, Cart-Het, and Cart-KO mice.
  • Table S1. Sequence of primers required for genotyping mice.
  • Table S2. Sequences of primers and probes for qPCR analyses.

[Download PDF]

Technical Details

Format: Adobe Acrobat PDF

Size: 666 KB

*These authors contributed equally to this work.

†To whom correspondence should be addressed. E-mail, wenhan.chang{at}

Citation: W. Chang, C. Tu, T.-H. Chen, D. Bikle, D. Shoback, The Extracellular Calcium-Sensing Receptor (CaSR) Is a Critical Modulator of Skeletal Development. Sci. Signal. 1, ra1 (2008).

© 2008 American Association for the Advancement of Science

To Advertise     Find Products

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882